Anti-Clostridium tetani tetX/Tetanus toxin Reference Antibody (SAA0800)

Anti-Clostridium tetani tetX/Tetanus toxin Reference Antibody (SAA0800)

  • Catalog number: BS12048
  • Availability: In Stock
  • $326.00

  • Ex Tax: $326.00


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Description: Anti-Clostridium tetani tetX/Tetanus toxin (SAA0800) (BS12048) is a research-grade recombinant antibody targeting tetX/Tetanus toxin. Produced in mammalian cells with native-like glycosylation.
Highlights:
• Research Grade — For PK/PD studies, assay development, and ADA research.
• Native Glycosylation — Mammalian expression ensures native-like patterns.
Host species: Human
Isotype: IgG1
Species reactivity: Clostridiumtetani(strainMassachusetts/E88)
Immunogen:
Form: Liquid
Storage instructions:
Storage buffer: 0.01M PBS, pH7.4.
Concentration: 1mg/ml
Purity: >95% as determined by SDS-PAGE.
Clonality: Monoclonal
Applications: Research Grade Biosimilar
Target: tetX/Tetanustoxin
Purification: Protein A/G purified from cell culture supernatant.
Endotoxin level: <1EU/mg, determined by LAL gel clotting assay
Expression system: Mammalian Cells
Stability and Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Alternative Names: TRN0010,TT0067
Background: Tetanus toxin (tetX) is a ~150 kDa protein. Tetanus toxin acts by inhibiting neurotransmitter release. It binds to peripheral neuronal synapses, is internalized and moves by retrograde transport up the axon into the spinal cord where it can move between postsynaptic and presynaptic neurons. It inhibits neurotransmitter release by acting as a zinc endopeptidase that catalyzes the hydrolysis of the '76-Gln-|-Phe-77' bond of synaptobrevin-2.
Note: For research use only. Not suitable for clinical or therapeutic use.

Images

  • SDS-PAGE for Anti-Clostridium tetani tetX/Tetanus toxin Reference Antibody (SAA0800)
    SDS-PAGE

    SDS-PAGE for Research Grade Anti-Clostridium tetani tetX/Tetanus toxin (SAA0800).

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