Anti-Human CD87/PLAUR/uPAR Antibody (8B12)

Description: Anti-Human CD87/PLAUR/uPAR Antibody (8B12) [8B12] (RA13831) is a mouse monoclonal antibody detecting PLAUR in ELISA, SPR. Suitable for Human.
Host species: Mouse
Isotype: IgG2a, kappa
Species reactivity: Human
Form: Liquid
Storage buffer: 0.01M PBS, pH 7.4.
Concentration: 1 mg/ml
Purity: >95% as determined by SDS-PAGE.
Clonality: Monoclonal
Applications: ELISA, SPR
Target: PLAUR, MO3, uPAR, CD87, Urokinase plasminogen activator surface receptor, Monocyte activation antigen Mo3
Purification: Protein A/G purified from cell culture supernatant.
Endotoxin level: Please contact with the lab for this information.
Stability and Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Alternative Names:
Background: Urokinase plasminogen activator surface receptor (CD87/PLAUR) is a ~36 kDa protein. Acts as a receptor for urokinase plasminogen activator. Plays a role in localizing and promoting plasmin formation. Mediates the proteolysis-independent signal transduction activation effects of U-PA. It is subject to negative-feedback regulation by U-PA which cleaves it into an inactive form.
References:
1. Bass, R. et al. (2005) The Journal of biological chemistry 280, 14811-8. PMID: 15677461
Note: For research use only.