Anti-ZIKV Envelope protein E/DIII domain Antibody (Z004)

Description: Anti-ZIKV Envelope protein E/DIII domain Antibody (Z004) [Z004] (RA14014) is a human monoclonal antibody detecting Envelope protein E in ELISA, FCM. Suitable for Zika virus (ZIKV) and Dengue virus 1.
Highlights:
• Flow Cytometry — Validated for flow cytometry applications.
Host species: Human
Isotype: IgG1, kappa
Species reactivity: Zika virus (ZIKV), Dengue virus 1, Dengue virus type 1 (strain Nauru/West Pac/1974) (DENV-1)
Form: Liquid
Storage buffer: 0.01M PBS, pH 7.4.
Concentration: 1 mg/ml
Purity: >95% as determined by SDS-PAGE.
Clonality: Monoclonal
Applications: ELISA, FCM
Target: Genome polyprotein, Envelope protein E
Purification: Protein A/G purified from cell culture supernatant.
Endotoxin level: Please contact with the lab for this information.
Stability and Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Alternative Names:
Background: Genome polyprotein (Envelope protein E) is a ~378 kDa protein. Capsid protein C self-assembles to form an icosahedral capsid about 30 nm in diameter. The capsid encapsulates the genomic RNA (Probable). Plays a role in virus budding by binding to the host cell membrane and packages the viral RNA into a nucleocapsid that forms the core of the mature virus particle. During virus entry, may induce genome penetration into the host cytoplasm after hemifusion induced by the surface proteins. Can migrate to the cell nucleus where it modulates host functions.
Note: For research use only.