Anti-Pig CD163 Antibody (2G01)

Description: Anti-Pig CD163 Antibody (2G01) [2G01] (RA14056) is a mouse monoclonal antibody detecting CD163 in ELISA. Suitable for Pig.
Host species: Mouse
Isotype: VHH-mFc (IgG2a)
Species reactivity: Pig
Form: Liquid
Storage buffer: 0.01M PBS, pH 7.4.
Concentration: 1 mg/ml
Purity: >95% as determined by SDS-PAGE.
Clonality: Monoclonal
Applications: ELISA
Target: Scavenger receptor cysteine-rich type 1 protein M130, Soluble CD163, sCD163, CD163, M130
Purification: Protein A/G purified from cell culture supernatant.
Endotoxin level: Please contact with the lab for this information.
Stability and Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Alternative Names:
Background: Scavenger receptor cysteine-rich type 1 protein M130 (CD163) is a ~120 kDa protein. Involved in clearance and endocytosis of hemoglobin/haptoglobin complexes by macrophages and may thereby protect tissues from free hemoglobin-mediated oxidative damage. May play a role in the uptake and recycling of iron, via endocytosis of hemoglobin/haptoglobin and subsequent breakdown of heme. Binds hemoglobin/haptoglobin complexes in a calcium-dependent and pH-dependent manner. Induces a cascade of intracellular signals that involves tyrosine kinase-dependent calcium mobilization, inositol triphosphate production and secretion of IL6 and CSF1. May play a role in the process of infection of porcine monocytes/macrophages by African swine fever virus (ASFV).
Note: For research use only.