Anti-Human ZBTB16 Antibody (C244)

Description: Anti-Human ZBTB16 Antibody (C244) [C244] (RA14149) is a mouse monoclonal antibody detecting ZBTB16 in ELISA, IF, IP. Suitable for Human.
Highlights:
• Multi-Application — Validated across multiple applications.
Host species: Mouse
Isotype: IgG2a, kappa
Species reactivity: Human
Form: Liquid
Storage buffer: 0.01M PBS, pH 7.4.
Concentration: 1 mg/ml
Purity: >95% as determined by SDS-PAGE.
Clonality: Monoclonal
Applications: ELISA, IF, IP
Target: ZBTB16, PLZF, ZNF145, Zinc finger and BTB domain-containing protein 16, Promyelocytic leukemia zinc finger protein, Zinc finger protein 145, Zinc finger protein PLZF
Purification: Protein A/G purified from cell culture supernatant.
Endotoxin level: Please contact with the lab for this information.
Stability and Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Alternative Names:
Background: Zinc finger and BTB domain-containing protein 16 (ZBTB16) is a ~74 kDa protein. Acts as a transcriptional repressor. Transcriptional repression may be mediated through recruitment of histone deacetylases to target promoters. May play a role in myeloid maturation and in the development and/or maintenance of other differentiated tissues. Probable substrate-recognition component of an E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins.
References:
1. Melnick, AM. et al. (2000) Molecular and cellular biology 20, 2075-86. PMID: 10688654
2. Lin, DY. et al. (2013) Journal of biomedical science 20, 98. PMID: 24359566
3. Furukawa, M. et al. (2003) Nature cell biology 5, 1001-7. PMID: 14528312
Note: For research use only.