Anti-BVDV Envelope glycoprotein E2 Antibody (SAA2088)

Description: Anti-BVDV Envelope glycoprotein E2 Antibody (SAA2088) [SAA2088] (RA14210) is a human monoclonal antibody detecting Envelope glycoprotein E2 in ELISA.
Host species: Human
Isotype: VHH-hFc
Species reactivity: Bovine viral diarrhea virus (isolate NADL) (BVDV) (Mucosal disease virus)
Form: Liquid
Storage buffer: 0.01M PBS, pH 7.4.
Concentration: 1 mg/ml
Purity: >95% as determined by SDS-PAGE.
Clonality: Monoclonal
Applications: ELISA
Target: Genome polyprotein, Envelope glycoprotein E2, gp55
Purification: Protein A/G purified from cell culture supernatant.
Endotoxin level: Please contact with the lab for this information.
Stability and Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Alternative Names:
Background: Genome polyprotein (Envelopeglycoprotein E2/gp55) is a ~449 kDa protein. Leader cysteine autoprotease that cleaves itself from the nascent polyprotein during translation of the viral mRNA. Once released, plays a role in the inhibition of host innate immune response by interacting with host IRF3 and inducing its proteasomal degradation.
References:
1. Chen, Z. et al. (2007) Virology 366, 277-92. PMID: 17531282
Note: For research use only.