InVivoMAb Anti-Human F9/Factor IX Antibody (10C12)

Description: InVivoMAb Anti-Human F9/Factor IX Antibody (10C12) [10C12] (RA14563) is a human monoclonal antibody detecting Plasma thromboplastin component in Blocking, ELISA. Suitable for Human.
Host species: Human
Isotype: IgG1, lambda
Species reactivity: Human
Form: Liquid
Storage buffer: 0.01M PBS, pH 7.4.
Concentration: 1 mg/ml
Purity: >95% as determined by SDS-PAGE.
Clonality: Monoclonal
Applications: Blocking,  ELISA
Target: Plasma thromboplastin component, F9, Christmas factor, Coagulation factor IX, PTC
Purification: Protein A/G purified from cell culture supernatant.
Endotoxin level: Please contact with the lab for this information.
Stability and Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Alternative Names:
Background: Coagulation factor IX (F9) is a ~51 kDa protein. Factor IX is a vitamin K-dependent plasma protein that participates in the intrinsic pathway of blood coagulation by converting factor X to its active form in the presence of Ca(2+) ions, phospholipids, and factor VIIIa.
References:
1. de la Salle, C. et al. (1993) Nouvelle revue francaise d'hematologie 35, 473-80. PMID: 8295821
2. Suehiro, K. et al. (1989) The Journal of biological chemistry 264, 21257-65. PMID: 2592373
3. Wang, S. et al. (2010) Journal of medicinal chemistry 53, 1473-82. PMID: 20121197
4. Wang, S. et al. (2010) Journal of medicinal chemistry 53, 1465-72. PMID: 20121198
5. Rawala-Sheikh, R. et al. (1992) Blood 79, 398-405. PMID: 1730085
6. Simioni, P. et al. (2009) The New England journal of medicine 361, 1671-5. PMID: 19846852
7. Cao, Q. et al. (2025) Nature 639, 816-824. PMID: 39880037
Note: For research use only. Not suitable for clinical or therapeutic use.