Anti-Human BRD1 IP Antibody (SAA0189)

Description: Anti-Human BRD1 IP Antibody (SAA0189) [SAA0189] (RA14584) is a mouse monoclonal antibody detecting BRD1 in ELISA, IF, IP. Suitable for Human.
Highlights:
• Multi-Application — Validated across multiple applications.
Host species: Mouse
Isotype: IgG2a
Species reactivity: Human
Form: Liquid
Storage buffer: 0.01M PBS, pH 7.4.
Concentration: 1 mg/ml
Purity: >95% as determined by SDS-PAGE.
Clonality: Monoclonal
Applications: ELISA, IF, IP
Target: Bromodomain and PHD finger-containing protein 2, BRPF2, BR140-like protein, BRL, BRD1, Bromodomain-containing protein 1
Purification: Protein A/G purified from cell culture supernatant.
Endotoxin level: Please contact with the lab for this information.
Stability and Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Alternative Names:
Background: Bromodomain-containing protein 1 (BRD1) is a ~119 kDa protein. Scaffold subunit of various histone acetyltransferase (HAT) complexes, such as the MOZ/MORF and HBO1 complexes, that acts as a regulator of hematopoiesis. Plays a key role in HBO1 complex by directing KAT7/HBO1 specificity towards histone H3 'Lys-14' acetylation (H3K14ac), thereby promoting erythroid differentiation.
References:
1. Doyon, Y. et al. (2006) Molecular cell 21, 51-64. PMID: 16387653
2. Mishima, Y. et al. (2011) Blood 118, 2443-53. PMID: 21753189
3. Qin, S. et al. (2011) The Journal of biological chemistry 286, 36944-55. PMID: 21880731
Note: For research use only.