Anti-Human BAZ2B IP Antibody (SAA0244)

Description: Anti-Human BAZ2B IP Antibody (SAA0244) [SAA0244] (RA14639) is a mouse monoclonal antibody detecting BAZ2B in ELISA, IF, IP, IP-MS. Suitable for Human.
Highlights:
• Multi-Application — Validated across multiple applications.
Host species: Mouse
Isotype: IgG2a
Species reactivity: Human
Form: Liquid
Storage buffer: 0.01M PBS, pH 7.4.
Concentration: 0.82 mg/ml
Purity: >95% as determined by SDS-PAGE.
Clonality: Monoclonal
Applications: ELISA, IF, IP, IP-MS
Target: hWALp4, BAZ2B, Bromodomain adjacent to zinc finger domain protein 2B, KIAA1476
Purification: Protein A/G purified from cell culture supernatant.
Endotoxin level: Please contact with the lab for this information.
Stability and Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Alternative Names:
Background: Bromodomain adjacent to zinc finger domain protein 2B (BAZ2B) is a ~240 kDa protein. Regulatory subunit of the ATP-dependent BRF-1 and BRF-5 ISWI chromatin remodeling complexes, which form ordered nucleosome arrays on chromatin and facilitate access to DNA during DNA-templated processes such as DNA replication, transcription, and repair. Both complexes regulate the spacing of nucleosomes along the chromatin and have the ability to slide mononucleosomes to the center of a DNA template. The BRF-1 ISWI chromatin remodeling complex has a lower ATP hydrolysis rate than the BRF-5 ISWI chromatin remodeling complex. Chromatin reader protein, which may play a role in transcriptional regulation via interaction with ISWI. Involved in positively modulating the rate of age-related behavioral deterioration.
References:
1. Oppikofer, M. et al. (2017) EMBO reports 18, 1697-1706. PMID: 28801535
2. Jones, MH. et al. (2000) Genomics 63, 40-5. PMID: 10662543
Note: For research use only.