Nivolumab ELISA Kit
- Catalog number: EL10141
- Availability: In Stock
$1,126.00
- Ex Tax: $1,126.00
- Stability and Storage: The stability of ELISA kit is determined by the loss rate of activity. The loss rate of this kit is less than 20% prior to the expiration date under appropriate storage condition.
- Detection method: Colorimetric
- Sample type: Plasma, Serum
- Assay type: Quantitative
- Sensitivity: 0.156 μg/ml
- Range: 0.31-5 μg/mL
- Recovery: 80-120%
- Background: Nivolumab is a human immunoglobulin G4 (IgG4) monoclonal antibody that binds to the programmed cell death 1 (PD-1) receptor and selectively blocks interaction with its programmed death ligands PD-L1 and PD-L2. Upregulation of PD-1 ligands occurs in some tumors and signalling through this pathway can contribute to inhibition of active T-cell immune surveillance of tumour tissue. The inhibitory effect of PD-1 and its ligands occurs through the promotion of apoptosis in antigen specific T cells while simultaneously blocking apoptosis in suppressor T cells. Blocking PD-1 activity has been shown to lead to decreased tumour growth in mouse tumour models.
- Alternative Names: BMS-936558, MDX-1106, ONO-4538, CAS: 946414-94-4
- Shipping: 2-8 ℃
- Specifications: Nivolumab
- Note: For Research Use Only.
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