Anti-Human ROR1 Antibody (P3A1)
- Catalog number: FC10048
- Availability: In Stock
$191.00
- Ex Tax: $191.00
- Description: Anti-Human ROR1 Antibody (P3A1) [P3A1] (FC10048) is a human monoclonal antibody detecting ROR1 in FCM. Suitable for Human.
Highlights:
• Flow Cytometry — Validated for flow cytometry applications. - Model: HX065207
- Name: Anti-Human ROR1 Antibody (P3A1)
- Host species: Human
- Isotype: VHH, hFc
- Conjugation: Unconjugated
- Species reactivity: Human
- Form: Liquid
- Storage buffer: 0.01M PBS, pH 7.4.
- Concentration: 1.95 mg/ml
- Purity: >95% as determined by SDS-PAGE.
- Clonality: Monoclonal
- Applications: FCM
- Target: Neurotrophic tyrosine kinase, receptor-related 1, Inactive tyrosine-protein kinase transmembrane receptor ROR1, NTRKR1, ROR1
- Purification: Protein A/G purified from cell culture supernatant.
- Endotoxin level: Please contact with the lab for this information.
- Stability and Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
- Background: Inactive tyrosine-protein kinase transmembrane receptor ROR1 (NTRKR1) is a ~104 kDa protein. Has very low kinase activity in vitro and is unlikely to function as a tyrosine kinase in vivo. Receptor for ligand WNT5A which activate downstream NFkB signaling pathway and may result in the inhibition of WNT3A-mediated signaling. In inner ear, crucial for spiral ganglion neurons to innervate auditory hair cells. Via IGFBP5 ligand, forms a complex with ERBB2 to enhance CREB oncogenic signaling.
References:
1. Bainbridge, TW. et al. (2014) PloS one 9, e102695. PMID: 25029443
2. Diaz-Horta, O. et al. (2016) Proceedings of the National Academy of Sciences of the United States of America 113, 5993-8. PMID: 2716235
3. Lin, W. et al. (2023) Nature communications 14, 1578. PMID: 36949068 - Note: For research use only.
Images
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SDS-PAGESDS-PAGE for Anti-Human ROR1 Antibody (P3A1)
Datasheet
