Anti-Human CD133/PROM1 Antibody (SAA0050)
- Catalog number: FC10148
- Availability: In Stock
$191.00
- Ex Tax: $191.00
- Description: Anti-Human CD133/PROM1 Antibody (SAA0050) [SAA0050] (FC10148) is a human monoclonal antibody detecting PROM1 in FCM. Suitable for Human.
Highlights:
• Flow Cytometry — Validated for flow cytometry applications. - Model: HT495107
- Name: Anti-Human CD133/PROM1 Antibody (SAA0050)
- Host species: Human
- Isotype: IgG1
- Conjugation: Unconjugated
- Species reactivity: Human
- Form: Liquid
- Storage buffer: 0.01M PBS, pH 7.4.
- Concentration: 1 mg/ml
- Purity: >95% as determined by SDS-PAGE.
- Clonality: Monoclonal
- Applications: FCM
- Target: PROML1, PROM1, Prominin-1, Antigen AC133, CD133, Prominin-like protein 1
- Purification: Protein A/G purified from cell culture supernatant.
- Endotoxin level: Please contact with the lab for this information.
- Stability and Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
- Background: Prominin-1 (CD133/PROM1) is a ~97 kDa protein. May play a role in cell differentiation, proliferation and apoptosis. Binds cholesterol in cholesterol-containing plasma membrane microdomains and may play a role in the organization of the apical plasma membrane in epithelial cells. During early retinal development acts as a key regulator of disk morphogenesis. Involved in regulation of MAPK and Akt signaling pathways. In neuroblastoma cells suppresses cell differentiation such as neurite outgrowth in a RET-dependent manner.
References:
1. Mak, AB. et al. (2014) Journal of molecular biology 426, 2175-82. PMID: 24556617
2. Takenobu, H. et al. (2011) Oncogene 30, 97-105. PMID: 20818439 - Note: For research use only.
Images
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BioactivitySEC-HPLC detection for Anti-Human CD133/PROM1 Antibody (ABS1140).
