Anti-Human CD140a/PDGFRA Antibody (SAA0057)
- Catalog number: FC10161
- Availability: In Stock
$191.00
- Ex Tax: $191.00
- Description: Anti-Human CD140a/PDGFRA Antibody (SAA0057) [SAA0057] (FC10161) is a human monoclonal antibody detecting PDGFRA in FCM. Suitable for Human.
Highlights:
• Flow Cytometry — Validated for flow cytometry applications. - Model: HB927207
- Name: Anti-Human CD140a/PDGFRA Antibody (SAA0057)
- Host species: Human
- Isotype: IgG2, kappa
- Conjugation: Unconjugated
- Species reactivity: Human
- Form: Liquid
- Storage buffer: 0.01M PBS, pH 7.4.
- Concentration: 1 mg/ml
- Purity: >95% as determined by SDS-PAGE.
- Clonality: Monoclonal
- Applications: FCM
- Target: PDGFR2, Platelet-derived growth factor receptor alpha, RHEPDGFRA, Alpha platelet-derived growth factor receptor, PDGFR-2, Platelet-derived growth factor alpha receptor, Platelet-derived growth factor receptor 2, PDGF-R-alpha, Alpha-type platelet-derived growth factor receptor, CD140a antigen, CD140 antigen-like family member A, PDGFRA, PDGFR-alpha, CD140a
- Purification: Protein A/G purified from cell culture supernatant.
- Endotoxin level: Please contact with the lab for this information.
- Stability and Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
- Background: Platelet-derived growth factor receptor alpha (CD140a/PDGFRA) is a ~122 kDa protein. Tyrosine-protein kinase that acts as a cell-surface receptor for PDGFA, PDGFB and PDGFC and plays an essential role in the regulation of embryonic development, cell proliferation, survival and chemotaxis. Depending on the context, promotes or inhibits cell proliferation and cell migration. Plays an important role in the differentiation of bone marrow-derived mesenchymal stem cells. Required for normal skeleton development and cephalic closure during embryonic development. Required for normal development of the mucosa lining the gastrointestinal tract, and for recruitment of mesenchymal cells and normal development of intestinal villi.
- Note: For research use only.
Images
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BioactivitySEC-HPLC detection for Anti-Human CD140a/PDGFRA Antibody (ABS0556).
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Flow CytometryFlow-cytometry using anti-human CD140a antibody. Human MG-63 cell line were stained with an irrelevant antibody (Green Histogram) or an anti-human CD140a antibody monoclonal antibody (Catalog # HB927207 , Red Histogram) at a concentration of 5 µg/ml for 30 mins at RT. After washing, bound antibody was detected using a FITC conjugated goat anti-human antibody (Catalog # HF690414) and cells analysed on a NovoCyte Flow Cytometer.n
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Western blotWestern blot analysis was performed using anti-CD140a/PDGFRA monoclonal antibody at 1μg/ml on various samples.
Lane 1: recombinant human CD140a/PDGFRA (Catalog No: PH13335)
