Anti-Human CD262/TNFRSF10B/TRAIL-R2 Antibody (SAA0084)
- Catalog number: FC10275
- Availability: In Stock
$191.00
- Ex Tax: $191.00
- Description: Anti-Human CD262/TNFRSF10B/TRAIL-R2 Antibody (SAA0084) [SAA0084] (FC10275) is a human monoclonal antibody detecting TRAIL-R2 in FCM. Suitable for Human.
Highlights:
• Flow Cytometry — Validated for flow cytometry applications. - Model: HT348107
- Name: Anti-Human CD262/TNFRSF10B/TRAIL-R2 Antibody (SAA0084)
- Host species: Human
- Isotype: IgG1, kappa
- Conjugation: Unconjugated
- Species reactivity: Human
- Form: Liquid
- Storage buffer: 0.01M PBS, pH 7.4.
- Concentration: 1 mg/ml
- Purity: >95% as determined by SDS-PAGE.
- Clonality: Monoclonal
- Applications: FCM
- Target: TRAILR2, TRAIL-R2, Death receptor 5, CD262, DR5, Tumor necrosis factor receptor superfamily member 10B, ZTNFR9, TRAIL receptor 2, TRICK2, TNFRSF10B, KILLER, TNF-related apoptosis-inducing ligand receptor 2
- Purification: Protein A/G purified from cell culture supernatant.
- Endotoxin level: Please contact with the lab for this information.
- Stability and Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
- Background: Tumor necrosis factor receptor superfamily member 10B (CD262/TRAIL-R2) is a ~47 kDa protein. Receptor for the cytotoxic ligand TNFSF10/TRAIL. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. Promotes the activation of NF-kappa-B. Essential for ER stress-induced apoptosis.
References:
1. Hymowitz, SG. et al. (1999) Molecular cell 4, 563-71. PMID: 10549288 - Note: For research use only.
Images
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SDS-PAGESDS-PAGE for Anti-Human CD262/TNFRSF10B/TRAIL-R2 Antibody (SAA0084)
