Anti-Human CD273/PD-L2/PDCD1LG2 Antibody (24F.10C12)
- Catalog number: FC10283
- Availability: In Stock
$191.00
- Ex Tax: $191.00
- Description: Anti-Human CD273/PD-L2/PDCD1LG2 Antibody (24F.10C12) [24F.10C12] (FC10283) is a mouse monoclonal antibody detecting PD-L2 in FCM. Suitable for Human.
Highlights:
• Flow Cytometry — Validated for flow cytometry applications. - Model: HV809107
- Name: Anti-Human CD273/PD-L2/PDCD1LG2 Antibody (24F.10C12)
- Host species: Mouse
- Isotype: IgG1, kappa
- Conjugation: Unconjugated
- Species reactivity: Human
- Form: Liquid
- Storage buffer: 0.01M PBS, pH 7.4.
- Concentration: 1 mg/ml
- Purity: >95% as determined by SDS-PAGE.
- Clonality: Monoclonal
- Applications: FCM
- Target: PDCD1 ligand 2, B7-DC, PD-L2, PDCD1LG2, PDCD1L2, PDL2, Butyrophilin B7-DC, Programmed death ligand 2, Programmed cell death 1 ligand 2, CD273, B7DC, PD-1 ligand 2
- Purification: Protein A/G purified from cell culture supernatant.
- Endotoxin level: Please contact with the lab for this information.
- Stability and Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
- Background: Programmed cell death 1 ligand 2 (CD273/PD-L2) is a ~30 kDa protein. Plays a critical role in induction and maintenance of immune tolerance to self. Acts as a ligand for the inhibitory receptor PDCD1/PD-1, inhibiting T-cell proliferation by blocking cell cycle progression and cytokine production.
References:
1. Latchman, Y. et al. (2001) Nature immunology 2, 261-8. PMID: 11224527
2. Brown, JA. et al. (2003) Journal of immunology (Baltimore, Md. : 1950) 170, 1257-66. PMID: 12538684 - Note: For research use only.
Images
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SDS-PAGESDS-PAGE for Anti-Human CD273/PD-L2/PDCD1LG2 Antibody (24F.10C12)
