Anti-Human CD357/TNFRSF18/GITR Antibody (hu6C8)

Size

50 µg

100 µg (+$179.00)

Qty

Description: Anti-Human CD357/TNFRSF18/GITR Antibody (hu6C8) [hu6C8] (FC10345) is a human monoclonal antibody detecting TNFRSF18 in FCM. Suitable for Human.
Highlights:
• Flow Cytometry — Validated for flow cytometry applications.
Model: HV475207
Name: Anti-Human CD357/TNFRSF18/GITR Antibody (hu6C8)
Host species: Human
Isotype: IgG1, kappa
Conjugation: Unconjugated
Species reactivity: Human
Form: Liquid
Storage buffer: 0.01M PBS, pH 7.4.
Concentration: 3.5 mg/ml
Purity: >95% as determined by SDS-PAGE.
Clonality: Monoclonal
Applications: FCM
Target: Activation-inducible TNFR family receptor, GITR, TNFRSF18, CD357, Tumor necrosis factor receptor superfamily member 18, AITR, Glucocorticoid-induced TNFR-related protein
Purification: Protein A/G purified from cell culture supernatant.
Endotoxin level: Please contact with the lab for this information.
Stability and Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Background: Tumor necrosis factor receptor superfamily member 18 (CD357/GITR) is a ~26 kDa protein. Receptor for TNFSF18. Seems to be involved in interactions between activated T-lymphocytes and endothelial cells and in the regulation of T-cell receptor-mediated cell death. Mediated NF-kappa-B activation via the TRAF2/NIK pathway.
Note: For research use only.

Bioactivity

SEC-HPLC detection for Anti-Human CD357/TNFRSF18/GITR Antibody (hu6C8).
Flow Cytometry

Flow-cytometry using anti-human CD357 antibody. Human RPMI-8226 cell line were stained with an irrelevant antibody (Green Histogram) or an anti-human CD357 antibody monoclonal antibody (Catalog # HV475207 , Red Histogram) at a concentration of 20 µg/ml for 30 mins at RT. After washing, bound antibody was detected using a FITC conjugated goat anti-human antibody (Catalog # HF690414) and cells analysed on a NovoCyte Flow Cytometer.n

Datasheet

$191.00