Anti-Human CD39/ENTPD1 Antibody (SRF367)
- Catalog number: FC10363
- Availability: In Stock
$196.00
- Ex Tax: $196.00
- Description: Anti-Human CD39/ENTPD1 Antibody (SRF367) [SRF367] (FC10363) is a mouse monoclonal antibody detecting ENTPD1 in FCM. Suitable for Human.
Highlights:
• Flow Cytometry — Validated for flow cytometry applications. - Model: HW564107
- Name: Anti-Human CD39/ENTPD1 Antibody (SRF367)
- Host species: Mouse
- Isotype: IgG1, kappa
- Conjugation: Unconjugated
- Species reactivity: Human
- Form: Liquid
- Storage buffer: 0.01M PBS, pH 7.4.
- Concentration: 1 mg/ml
- Purity: >95% as determined by SDS-PAGE.
- Clonality: Monoclonal
- Applications: FCM
- Target: Ecto-ATP diphosphohydrolase 1, NTPDase 1, ENTPD1, Ecto-ATPase 1, Ecto-apyrase, Ecto-ATPDase 1, Ectonucleoside triphosphate diphosphohydrolase 1, CD39, Lymphoid cell activation antigen
- Purification: Protein A/G purified from cell culture supernatant.
- Endotoxin level: Please contact with the lab for this information.
- Stability and Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
- Background: Ectonucleoside triphosphate diphosphohydrolase 1 (CD39/ENTPD1) is a ~57 kDa protein. Catalyzes the hydrolysis of nucleoside triphosphates (NTPs) and diphosphates (NDPs) (Probable). The enzyme sequentially removes phosphate groups in two successive steps, converting NTPs to nucleoside monophosphates (NMPs) via NDP intermediates (Probable). This activity contributes to the regulation of extracellular levels of nucleotides (Probable). By hydrolyzing proinflammatory ATP and platelet-activating ADP to AMP, it blocks platelet aggregation and supports blood flow.
References:
1. Christoforidis, S. et al. (1995) European journal of biochemistry 234, 66-74. PMID: 852967
2. Wang, TF. et al. (1996) The Journal of biological chemistry 271, 9898-901. PMID: 8626624
3. Kaczmarek, E. et al. (1996) The Journal of biological chemistry 271, 33116-22. PMID: 895516
4. Robson, SC. et al. (1997) The Journal of experimental medicine 185, 153-63. PMID: 8996251 - Note: For research use only.
Images
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BioactivitySEC-HPLC detection for Anti-Human CD39/ENTPD1 Antibody (SRF367).
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Flow CytometryFlow-cytometry using anti-human CD39 antibody.CD39 Transfected CHO cells were stained with an irrelevant antibody (Blue Histogram) or an anti-human CD39 antibody monoclonal antibody (Catalog # HW564107 ,Green Histogram) at a concentration of 5 µg/ml for 30 mins at RT. After washing, bound antibody was detected using a FITC conjugated goat anti-mouse antibody (Catalog # MF690414) and cells analysed on a NovoCyte Flow Cytometer.
