Anti-Human ACVRL1 Antibody (SAA0129)
- Catalog number: FC10479
- Availability: In Stock
$191.00
- Ex Tax: $191.00
- Description: Anti-Human ACVRL1 Antibody (SAA0129) [SAA0129] (FC10479) is a human monoclonal antibody detecting ACVRL1 in FCM, Neutralization, WB. Suitable for Human.
Highlights:
• Multi-Application — Validated across multiple applications.
• Flow Cytometry — Validated for flow cytometry applications. - Model: HW651107
- Name: Anti-Human ACVRL1 Antibody (SAA0129)
- Host species: Human
- Isotype: IgG2, kappa
- Conjugation: Unconjugated
- Species reactivity: Human
- Form: Liquid
- Storage buffer: 0.01M PBS, pH 7.4.
- Concentration: 1 mg/ml
- Purity: >95% as determined by SDS-PAGE.
- Clonality: Monoclonal
- Applications: FCM, Neutralization, WB
- Target: Serine/threonine-protein kinase receptor R3, ACVRL1, Activin receptor-like kinase 1, ALK-1, ACVRLK1, ALK1, SKR3, TGF-B superfamily receptor type I, TSR-I
- Purification: Protein A/G purified from cell culture supernatant.
- Endotoxin level: Please contact with the lab for this information.
- Stability and Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
- Background: Activin receptor type-1-like (ACVRL1/ALK-1) is a ~56 kDa protein. Type I receptor for TGF-beta family ligands BMP9/GDF2 and BMP10 and important regulator of normal blood vessel development. On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. May bind activin as well.
- Note: For research use only.
Images
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SDS-PAGESDS-PAGE for Anti-Human ACVRL1 Antibody (SAA0129)
Datasheet
