Anti-Mouse CD8a/Lyt2 Antibody (19.178#)
- Catalog number: FC10568
- Availability: In Stock
$196.00
- Ex Tax: $196.00
- Description: Anti-Mouse CD8a/Lyt2 Antibody (19.178#) [19.178#] (FC10568) is a rat monoclonal antibody detecting CD8a in FCM, IF, IP. Suitable for Mouse.
Highlights:
• Multi-Application — Validated across multiple applications.
• Flow Cytometry — Validated for flow cytometry applications. - Model: MF815507
- Name: Anti-Mouse CD8a/Lyt2 Antibody (19.178#)
- Host species: Rat
- Isotype: IgG1, kappa
- Conjugation: Unconjugated
- Species reactivity: Mouse
- Form: Liquid
- Storage buffer: 0.01M PBS, pH 7.4.
- Concentration: 1 mg/ml
- Purity: >95% as determined by SDS-PAGE.
- Clonality: Monoclonal
- Applications: FCM, IF, IP
- Target: T-cell surface glycoprotein CD8 alpha chain, T-cell surface glycoprotein Lyt-2, CD8a, Cd8a, Lyt-2, Lyt2,CD8
- Purification: Protein A/G purified from cell culture supernatant.
- Endotoxin level: Please contact with the lab for this information.
- Stability and Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
- Background: T-cell surface glycoprotein CD8 alpha chain (CD8a/Lyt2) is a ~27 kDa protein. Integral membrane glycoprotein that plays an essential role in the immune response and serves multiple functions in responses against both external and internal offenses. In T-cells, functions primarily as a coreceptor for MHC class I molecule:peptide complex. The antigens presented by class I peptides are derived from cytosolic proteins while class II derived from extracellular proteins. Interacts simultaneously with the T-cell receptor (TCR) and the MHC class I proteins presented by antigen presenting cells (APCs). In turn, recruits the Src kinase LCK to the vicinity of the TCR-CD3 complex.
- Note: For research use only.
Images
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SDS-PAGESDS-PAGE for Anti-Mouse CD8a/Lyt2 Antibody (19.178#)
