Anti-Mouse CD11b/ITGAM Antibody (M1/70)
- Catalog number: FC10579
- Availability: In Stock
$118.00
- Ex Tax: $118.00
- Description: Anti-Mouse CD11b/ITGAM Antibody (M1/70) [M1/70] (FC10579) is a rat monoclonal antibody detecting ITGAM in FCM, ICC, IHC, IP. Suitable for Human and Mouse.
Highlights:
• Multi-Application — Validated across multiple applications.
• Flow Cytometry — Validated for flow cytometry applications. - Model: MY474307
- Name: Anti-Mouse CD11b/ITGAM Antibody (M1/70)
- Host species: Rat
- Isotype: IgG2b, kappa
- Conjugation: Unconjugated
- Species reactivity: Human, Mouse
- Form: Liquid
- Storage buffer: 0.01M PBS, pH 7.4.
- Concentration: 1 mg/ml
- Purity: >95% as determined by SDS-PAGE.
- Clonality: Monoclonal
- Applications: FCM, ICC, IHC, IP
- Target: CR-3 alpha chain, Cell surface glycoprotein MAC-1 subunit alpha, Leukocyte adhesion receptor MO1, ITGAM, CD11b, CD11 antigen-like family member B, Integrin alpha-M, CR3A, CD11B, Neutrophil adherence receptor
- Purification: Protein A/G purified from cell culture supernatant.
- Endotoxin level: Please contact with the lab for this information.
- Stability and Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
- Background: Integrin alpha-M (CD11b/ITGAM) is a ~127 kDa protein. Integrin ITGAM/ITGB2 is implicated in various adhesive interactions of monocytes, macrophages and granulocytes as well as in mediating the uptake of complement-coated particles and pathogens. It is identical with CR-3, the receptor for the iC3b fragment of the third complement component. It probably recognizes the R-G-D peptide in C3b. Integrin ITGAM/ITGB2 is also a receptor for fibrinogen, and factor X. It recognizes P1 and P2 peptides of fibrinogen gamma chain.
References:
1. Wakselman, S. et al. (2008) The Journal of neuroscience : the official journal of the Society for Neuroscience 28, 8138-43. PMID: 18685038 - Note: For research use only.
Images
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SDS-PAGESDS-PAGE for Anti-Mouse CD11b/ITGAM Antibody (M1/70)
