Anti-Mouse CD230 Antibody (POM1)
- Catalog number: FC10622
- Availability: In Stock
$191.00
- Ex Tax: $191.00
- Description: Anti-Mouse CD230 Antibody (POM1) [POM1] (FC10622) is a mouse monoclonal antibody detecting CD230 in ELISA, FCM. Suitable for Human, Mouse, Bovine, and Hamster.
Highlights:
• Flow Cytometry — Validated for flow cytometry applications.
• Multi-Species — Cross-reactive for translational research. - Model: MY392307
- Name: Anti-Mouse CD230 Antibody (POM1)
- Host species: Mouse
- Isotype: IgG2a, kappa
- Conjugation: Unconjugated
- Species reactivity: Human, Mouse, Bovine, Hamster
- Form: Liquid
- Storage buffer: 0.01M PBS, pH 7.4.
- Concentration: 1 mg/ml
- Purity: >95% as determined by SDS-PAGE.
- Clonality: Monoclonal
- Applications: ELISA, FCM
- Target: Major prion protein, PrP, PrP27-30, PrP33-35C, CD230, Prnp, Prn-p
- Purification: Protein A/G purified from cell culture supernatant.
- Endotoxin level: Please contact with the lab for this information.
- Stability and Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
- Background: Major prion protein (CD230/PRNP) is a ~27 kDa protein. Its primary physiological function is unclear. May play a role in neuronal development and synaptic plasticity. May be required for neuronal myelin sheath maintenance. May promote myelin homeostasis through acting as an agonist for ADGRG6 receptor. May play a role in iron uptake and iron homeostasis.
References:
1. Mani, K. et al. (2003) The Journal of biological chemistry 278, 38956-65. PMID: 12732622
2. Steele, AD. et al. (2006) Proceedings of the National Academy of Sciences of the United States of America 103, 3416-21. PMID: 16492732
3. Laurén, J. et al. (2009) Nature 457, 1128-32. PMID: 19242475
4. Singh, A. et al. (2009) PloS one 4, e6115. PMID: 19568430 - Note: For research use only.
Images
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Western blotWestern blot analysis was performed using anti-CD230/PRNP monoclonal antibody at 1ug/mL on various samples.
Lane 1: recombinant human CD230/PRNP (Catalog No: PH15429)
Lane 2: negative control
Datasheet
