Anti-Mouse DLL4 Antibody (21H3RK)
- Catalog number: FC10657
- Availability: In Stock
$191.00
- Ex Tax: $191.00
- Description: Anti-Mouse DLL4 Antibody (21H3RK) [21H3RK] (FC10657) is a mouse monoclonal antibody detecting DLL4 in ELISA, FCM. Suitable for Human, Mouse, and Monkey.
Highlights:
• Flow Cytometry — Validated for flow cytometry applications.
• Multi-Species — Cross-reactive for translational research. - Model: MV571107
- Name: Anti-Mouse DLL4 Antibody (21H3RK)
- Host species: Mouse
- Isotype: IgG1, kappa
- Conjugation: Unconjugated
- Species reactivity: Human, Mouse, Monkey
- Form: Liquid
- Storage buffer: 0.01M PBS, pH 7.4.
- Concentration: 1 mg/ml
- Purity: >95% as determined by SDS-PAGE.
- Clonality: Monoclonal
- Applications: ELISA, FCM
- Target: Delta-like protein 4, Drosophila Delta homolog 4, Delta4, DLL4
- Purification: Protein A/G purified from cell culture supernatant.
- Endotoxin level: Please contact with the lab for this information.
- Stability and Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
- Background: Delta-like protein 4 (DLL4) is a ~74 kDa protein. Involved in the Notch signaling pathway as Notch ligand. Activates NOTCH1 and NOTCH4. Involved in angiogenesis; negatively regulates endothelial cell proliferation and migration and angiogenic sprouting. Essential for retinal progenitor proliferation. Required for suppressing rod fates in late retinal progenitors as well as for proper generation of other retinal cell types.
References:
1. Yoneya, T. et al. (2001) Journal of biochemistry 129, 27-34. PMID: 11134954
2. Luo, H. et al. (2012) Proceedings of the National Academy of Sciences of the United States of America 109, E553-62. PMID: 22323600 - Note: For research use only.
Images
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SDS-PAGESDS-PAGE for Anti-Mouse DLL4 Antibody (21H3RK)
Datasheet
