Anti-Mouse CD100/SEMA4D Antibody (SAA0332)
- Catalog number: FC10687
- Availability: In Stock
$196.00
- Ex Tax: $196.00
- Description: Anti-Mouse CD100/SEMA4D Antibody (SAA0332) [SAA0332] (FC10687) is a mouse monoclonal antibody detecting SEMA4D in FCM, FuncS, Neutralization. Suitable for Mouse.
Highlights:
• Multi-Application — Validated across multiple applications.
• Flow Cytometry — Validated for flow cytometry applications. - Model: MV563107
- Name: Anti-Mouse CD100/SEMA4D Antibody (SAA0332)
- Host species: Mouse
- Isotype: IgG1, kappa
- Conjugation: Unconjugated
- Species reactivity: Mouse
- Form: Liquid
- Storage buffer: 0.01M PBS, pH 7.4.
- Concentration: 1.84 mg/ml
- Purity: >95% as determined by SDS-PAGE.
- Clonality: Monoclonal
- Applications: FCM, FuncS, Neutralization
- Target: A8, Semaphorin-4D, GR3, BB18, SEMAJ, C9orf164, CD100, SEMA4D
- Purification: Protein A/G purified from cell culture supernatant.
- Endotoxin level: Please contact with the lab for this information.
- Stability and Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
- Background: Semaphorin-4D (CD100/SEMA4D) is a ~95 kDa protein. Cell surface receptor for PLXNB1 and PLXNB2 that plays an important role in cell-cell signaling. Regulates GABAergic synapse development. Promotes the development of inhibitory synapses in a PLXNB1-dependent manner. Modulates the complexity and arborization of developing neurites in hippocampal neurons by activating PLXNB1 and interaction with PLXNB1 mediates activation of RHOA. Promotes the migration of cerebellar granule cells.
References:
1. Kuzirian, MS. et al. (2013) The Journal of neuroscience : the official journal of the Society for Neuroscience 33, 8961-73. PMID: 23699507
2. McDermott, JE. et al. (2018) Molecular and cellular neurosciences 92, 50-66. PMID: 2998148
3. Deng, S. et al. (2007) The Journal of neuroscience : the official journal of the Society for Neuroscience 27, 6333-47. PMID: 17554007 - Note: For research use only.
Images
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SDS-PAGESDS-PAGE for Anti-Mouse CD100/SEMA4D Antibody (SAA0332)
