Anti-Mouse NKG2D Antibody (CX5)
- Catalog number: FC10700
- Availability: In Stock
$191.00
- Ex Tax: $191.00
- Description: Anti-Mouse NKG2D Antibody (CX5) [CX5] (FC10700) is a rat monoclonal antibody detecting Nkg2d in Blocking, ELISA, FCM. Suitable for Mouse.
Highlights:
• Multi-Application — Validated across multiple applications.
• Flow Cytometry — Validated for flow cytometry applications. - Model: MB123207
- Name: Anti-Mouse NKG2D Antibody (CX5)
- Host species: Rat
- Isotype: IgG1, kappa
- Conjugation: Unconjugated
- Species reactivity: Mouse
- Form: Liquid
- Storage buffer: 0.01M PBS, pH 7.4, 0.09% Sodium azide.
- Concentration: 1 mg/ml
- Purity: >95% as determined by SDS-PAGE.
- Clonality: Monoclonal
- Applications: Blocking, ELISA, FCM
- Target: NKG2-D type II integral membrane protein, Killer cell lectin-like receptor subfamily K member 1, NK cell receptor D, NKG2-D-activating NK receptor, CD314, Klrk1, Nkg2d
- Purification: Protein A/G purified from cell culture supernatant.
- Endotoxin level: Please contact with the lab for this information.
- Stability and Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
- Background: NKG2-D type II integral membrane protein (CD314/KLRK1) is a ~26 kDa protein. Functions as an activating and costimulatory receptor involved in immunosurveillance upon binding to various cellular stress-inducible ligands displayed at the surface of autologous tumor cells and virus-infected cells. Provides both stimulatory and costimulatory innate immune responses on activated killer (NK) cells, leading to cytotoxic activity. Acts as a costimulatory receptor for T-cell receptor (TCR) in CD8(+) T-cell-mediated adaptive immune responses by amplifying T-cell activation. Stimulates perforin-mediated elimination of ligand-expressing tumor cells. Signaling involves calcium influx, culminating in the expression of TNF.
- Note: For research use only.
Images
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SDS-PAGESDS-PAGE for Anti-Mouse NKG2D Antibody (CX5)
Datasheet
