Anti-Human BMP10 Antibody (SAA0428)
- Catalog number: FC10766
- Availability: In Stock
$196.00
- Ex Tax: $196.00
- Description: Anti-Human BMP10 Antibody (SAA0428) [SAA0428] (FC10766) is a mouse monoclonal antibody detecting BMP10 in ELISA, FCM. Suitable for Human.
Highlights:
• Flow Cytometry — Validated for flow cytometry applications. - Model: HF791107
- Name: Anti-Human BMP10 Antibody (SAA0428)
- Host species: Mouse
- Isotype: IgG2a, kappa
- Conjugation: Unconjugated
- Species reactivity: Human
- Form: Liquid
- Storage buffer: 0.01M PBS, pH 7.4.
- Concentration: 1.54 mg/ml
- Purity: >95% as determined by SDS-PAGE.
- Clonality: Monoclonal
- Applications: ELISA, FCM
- Target: BMP-10, Bone morphogenetic protein 10, BMP10
- Purification: Protein A/G purified from cell culture supernatant.
- Endotoxin level: Please contact with the lab for this information.
- Stability and Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
- Background: Bone morphogenetic protein 10 (BMP10) is a ~48 kDa protein. Required for maintaining the proliferative activity of embryonic cardiomyocytes by preventing premature activation of the negative cell cycle regulator CDKN1C/p57KIP and maintaining the required expression levels of cardiogenic factors such as MEF2C and NKX2-5. Acts as a ligand for ACVRL1/ALK1, BMPR1A/ALK3 and BMPR1B/ALK6, leading to activation of SMAD1, SMAD5 and SMAD8 transcription factors. Inhibits endothelial cell migration and growth. May reduce cell migration and cell matrix adhesion in breast cancer cell lines.
- Note: For research use only.
Images
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SDS-PAGESDS-PAGE for Anti-Human BMP10 Antibody (SAA0428)
Datasheet
