Anti-Staphylococcus aureus Protein A/SPA Antibody (SAA1452)
- Catalog number: FC10954
- Availability: In Stock
$196.00
- Ex Tax: $196.00
- Description: Anti-Staphylococcus aureus Protein A/SPA Antibody (SAA1452) [SAA1452] (FC10954) is a mouse monoclonal antibody detecting spa in ELISA, FCM, WB.
Highlights:
• Multi-Application — Validated across multiple applications.
• Flow Cytometry — Validated for flow cytometry applications. - Model: JN856107
- Name: Anti-Staphylococcus aureus Protein A/SPA Antibody (SAA1452)
- Host species: Mouse
- Isotype: IgG2a
- Conjugation: Unconjugated
- Species reactivity: Staphylococcus aureus (P38507), Staphylococcus aureus (strain N315) (P99134), Staphylococcus aureus (strain Mu50 / ATCC 700699) (P0A015)
- Form: Liquid
- Storage buffer: 0.01M PBS, pH 7.4.
- Concentration: 2.78 mg/ml
- Purity: >95% as determined by SDS-PAGE.
- Clonality: Monoclonal
- Applications: ELISA, FCM, WB
- Target: spa, Immunoglobulin G-binding protein A, Staphylococcal protein A
- Purification: Protein A/G purified from cell culture supernatant.
- Endotoxin level: Please contact with the lab for this information.
- Stability and Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
- Background: Immunoglobulin G-binding protein A (SPA) is a ~55 kDa protein. Plays a role in the inhibition of the host innate and adaptive immune responses. Possesses five immunoglobulin-binding domains that capture both the fragment crystallizable region (Fc region) and the Fab region (part of Ig that identifies antigen) of immunoglobulins. In turn, Staphylococcus aureus is protected from phagocytic killing via inhibition of Ig Fc region. In addition, the host elicited B-cell response is prevented due to a decrease of antibody-secreting cell proliferation that enter the bone marrow, thereby decreasing long-term antibody production. Inhibits osteogenesis by preventing osteoblast proliferation and expression of alkaline phosphatase, type I collagen, osteopontin and osteocalcin.
- Note: For research use only.
Images
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SDS-PAGESDS-PAGE for Anti-Staphylococcus aureus Protein A/SPA Antibody (SAA1452).
