Anti-Human CD307e/FCRL5 Reference Antibody (DFRF 4539A)
- Catalog number: BS12300
- Availability: In Stock
$370.00
- Ex Tax: $370.00
Description: Anti-Human CD307e/FCRL5 Antibody (DFRF 4539A) (BS12300) is a research-grade recombinant antibody targeting CD307. Produced in mammalian cells with native-like glycosylation.
Highlights:
• Research Grade — For PK/PD studies, assay development, and ADA research.
• Native Glycosylation — Mammalian expression ensures native-like patterns.
Host species: Human
Isotype: IgG1-kappa
Species reactivity: Human
Immunogen:
Form: Liquid
Storage instructions:
Storage buffer: 0.01M PBS, pH7.4.
Concentration: 1mg/ml
Purity: >95% as determined by SDS-PAGE.
Clonality: Monoclonal
Applications: Research Grade Biosimilar
Target: Fcreceptor-likeprotein5,FcR-likeprotein5,FcRL5,BXMAS1,Fcreceptorhomolog5,FcRH5,Immunereceptortranslocation-associatedprotein2,CD307e,FCRL5,FCRH5,IRTA2,UNQ503/PRO820
Purification: Protein A/G purified from cell culture supernatant.
Endotoxin level: <1EU/mg, determined by LAL gel clotting assay
Expression system: Mammalian Cells
Stability and Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Alternative Names: DFRF4539A,DFRF-4539A,DFRF4539A,RG7598,RG-7598,RG7598
Background: Fc receptor-like protein 5 (CD307e/FCRL5) is a ~106 kDa protein. Plays an important role in B-cell response to antigen that acts both as a negative or positive coreceptor. Inhibits B-cell receptor (BCR) signaling in the absence of CR2 stimulation but engagement with CR2 and the BCR lead to a superior calcium response compared to CR2 and BCR costimulation. May be involved in B-cell development and differentiation in peripheral lymphoid organs and may be useful markers of B-cell stages. May have an immunoregulatory role in marginal zone B-cells. May play a role in fertilization.
References:
1. Franco, A. et al. (2018) International immunology 30, 569-578. PMID: 30107486
Note: For research use only. Not suitable for clinical or therapeutic use.
Highlights:
• Research Grade — For PK/PD studies, assay development, and ADA research.
• Native Glycosylation — Mammalian expression ensures native-like patterns.
Host species: Human
Isotype: IgG1-kappa
Species reactivity: Human
Immunogen:
Form: Liquid
Storage instructions:
Storage buffer: 0.01M PBS, pH7.4.
Concentration: 1mg/ml
Purity: >95% as determined by SDS-PAGE.
Clonality: Monoclonal
Applications: Research Grade Biosimilar
Target: Fcreceptor-likeprotein5,FcR-likeprotein5,FcRL5,BXMAS1,Fcreceptorhomolog5,FcRH5,Immunereceptortranslocation-associatedprotein2,CD307e,FCRL5,FCRH5,IRTA2,UNQ503/PRO820
Purification: Protein A/G purified from cell culture supernatant.
Endotoxin level: <1EU/mg, determined by LAL gel clotting assay
Expression system: Mammalian Cells
Stability and Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Alternative Names: DFRF4539A,DFRF-4539A,DFRF4539A,RG7598,RG-7598,RG7598
Background: Fc receptor-like protein 5 (CD307e/FCRL5) is a ~106 kDa protein. Plays an important role in B-cell response to antigen that acts both as a negative or positive coreceptor. Inhibits B-cell receptor (BCR) signaling in the absence of CR2 stimulation but engagement with CR2 and the BCR lead to a superior calcium response compared to CR2 and BCR costimulation. May be involved in B-cell development and differentiation in peripheral lymphoid organs and may be useful markers of B-cell stages. May have an immunoregulatory role in marginal zone B-cells. May play a role in fertilization.
References:
1. Franco, A. et al. (2018) International immunology 30, 569-578. PMID: 30107486
Note: For research use only. Not suitable for clinical or therapeutic use.
Images
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BioactivityDetects recombinant human CD307e/FCRL5 (Catalog No: PH13732) in indirect ELISA
