Anti-Human MAGEA4 Reference Antibody (Imc-C103C)

Description: Anti-Human MAGEA4 Antibody (Imc-C103C) (BS12488) is a research-grade recombinant antibody targeting Cancer/testis antigen 1.4. Produced in mammalian cells with native-like glycosylation.
Highlights:
• Research Grade — For PK/PD studies, assay development, and ADA research.
• Native Glycosylation — Mammalian expression ensures native-like patterns.
Host species: Human
Isotype: IgG
Species reactivity: Human
Immunogen:
Form: Liquid
Storage instructions:
Storage buffer: 0.01M PBS, pH7.4.
Concentration: 1mg/ml
Purity: >95% as determined by SDS-PAGE.
Clonality:
Applications: Research Grade Biosimilar
Target: Cancer/testisantigen1.4,MAGEA4,MAGE4,CT1.4,Melanoma-associatedantigen4,MAGE-X2antigen,MAGE-41antigen,MAGE-4antigen
Purification: Protein A/G purified from cell culture supernatant.
Endotoxin level: <1EU/mg, determined by LAL gel clotting assay
Expression system: Mammalian Cells
Stability and Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Alternative Names: Imc-C103C,ImcC103C,ImcC103C
Background: Melanoma-associated antigen 4 (MAGEA4 (pMHC) & CD3) is a ~34 kDa protein. Regulates cell proliferation through the inhibition of cell cycle arrest at the G1 phase. Also negatively regulates p53-mediated apoptosis.
References:
1. Bhan, S. et al. (2012) Oncology reports 28, 1498-502. PMID: 22842486
Note: For research use only. Not suitable for clinical or therapeutic use.