Anti-Human CD20/MS4A1 Antibody (SAA2210)
- Catalog number: FC15117
- Availability: In Stock
$191.00
- Ex Tax: $191.00
- Description: Anti-Human CD20/MS4A1 Antibody (SAA2210) [SAA2210] (FC15117) is a human monoclonal antibody detecting MS4A1 in ELISA, FCM. Suitable for Human.
Highlights:
• Flow Cytometry — Validated for flow cytometry applications. - Model: HY257707
- Name: Anti-Human CD20/MS4A1 Antibody (SAA2210)
- Host species: Human
- Isotype: IgG1, kappa
- Species reactivity: Human
- Form: Liquid
- Storage buffer: 0.01M PBS, pH 7.4, 0.09% Sodium azide.
- Purity: >95% as determined by SDS-PAGE.
- Clonality: Monoclonal
- Applications: ELISA, FCM
- Target: B-lymphocyte surface antigen B1, Membrane-spanning 4-domains subfamily A member 1, MS4A1, Leukocyte surface antigen Leu-16, B-lymphocyte antigen CD20, Bp35, CD20
- Purification: Protein A/G purified from cell culture supernatant.
- Endotoxin level: Please contact with the lab for this information.
- Stability and Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
- Background: B-lymphocyte antigen CD20 (MS4A1) is a ~33 kDa protein. B-lymphocyte-specific membrane protein that plays a role in the regulation of cellular calcium influx necessary for the development, differentiation, and activation of B-lymphocytes. Functions as a store-operated calcium (SOC) channel component promoting calcium influx after activation by the B-cell receptor/BCR. CD20 is the therapeutic target of rituximab (MabThera) and obinutuzumab (Gazyva).
References:
1. Li, H. et al. (2003) The Journal of biological chemistry 278, 42427-34. PMID: 12920111
2. Tedder, TF. et al. (1985) Journal of immunology (Baltimore, Md. : 1950) 135, 973-9. PMID: 3925015
3. Bubien, JK. et al. (1993) The Journal of cell biology 121, 1121-32. PMID: 7684739
4. Polyak, MJ. et al. (2008) The Journal of biological chemistry 283, 18545-52. PMID: 18474602 - Note: For research use only.
Images
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SDS-PAGESDS-PAGE for Anti-Human CD20/MS4A1 Antibody (SAA2210)
