Anti-Human RHD Reference Antibody (Roledumab, RUO)

Description: Roledumab (BS10228) is a research-grade recombinant antibody targeting CD240D. Produced in mammalian cells with native-like glycosylation.
Highlights:
• Research Grade — For PK/PD studies, assay development, and ADA research.
• Native Glycosylation — Mammalian expression ensures native-like patterns.
Host species: Human
Isotype: IgG1-kappa
Species reactivity: Human
Immunogen:
Form: Liquid
Storage instructions:
Storage buffer: 0.01M PBS, pH7.4.
Concentration: 1mg/ml
Purity: >95% as determined by SDS-PAGE.
Clonality: Monoclonal
Applications: Research Grade Biosimilar
Target: CD240D,RHXIII,BloodgroupRh(D)polypeptide,Rhpolypeptide2,RhPII,RhesusDantigen,RHD
Purification: Protein A/G purified from cell culture supernatant.
Endotoxin level: <1EU/mg, determined by LAL gel clotting assay
Expression system: Mammalian Cells
Stability and Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Alternative Names: LFB-R593,CAS:1174008-79-7
Background: Blood group Rh(D) polypeptide (CD240D/RHD) is a ~45 kDa protein. May be part of an oligomeric complex which is likely to have a transport or channel function in the erythrocyte membrane.
Note: For research use only. Not suitable for clinical or therapeutic use.