Human EPO Recombinant Protein (C-His)
- Catalog number: PH10448
- Availability: In Stock
$298.00
- Ex Tax: $298.00
- Description: Recombinant Human EPO Protein, C-His (PH10448) expressed in Mammalian Cells, spanning Ala28-Arg193.
Highlights:
• His-Tagged — N-terminal 6×His tag for IMAC purification.
• Mammalian Expression — Proper folding and native glycosylation.
• High Purity — >90% purity verified by SDS-PAGE. - Form: Lyophilized
- Storage buffer: Lyophilized from a solution in PBS pH 7.4, 1mM EDTA, 4% Trehalose, 1% Mannitol.
- Purity: >90% as determined by SDS-PAGE.
- Applications: ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
- Endotoxin level: Please contact with the lab for this information.
- Expression system: Mammalian Cells
- Protein length: Ala28-Arg193
- Predicted molecular weight: 22.28 kDa
- Stability and Storage: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
- Reconstitution: Reconstitute in sterile water for a stock solution.A copy of datasheet will be provided with the products, please refer to it for details.
- Alternative Names: EPO, Erythropoietin, Epoetin
- Species: Homo sapiens (Human)
- Shipping: In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
- Background: Erythropoietin (EPO) is a ~21 kDa protein. Hormone involved in the regulation of erythrocyte proliferation and differentiation and the maintenance of a physiological level of circulating erythrocyte mass. Binds to EPOR leading to EPOR dimerization and JAK2 activation thereby activating specific downstream effectors, including STAT1 and STAT3.
References:
1. Kim, AR. et al. (2017) Cell 168, 1053-1064.e15. PMID: 28283061
2. Syed, RS. et al. (1998) Nature 395, 511-6. PMID: 9774108 - Note: For research use only.
Images
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SDS-PAGESDS-PAGE for Recombinant Human EPO Protein, C-His
