Anti-Human EpCAM/TROP1 Reference Antibody (Edrecolomab, RUO)

Description: Edrecolomab (BS10281) is a research-grade recombinant antibody targeting CD326. Produced in mammalian cells with native-like glycosylation.
Highlights:
• Research Grade — For PK/PD studies, assay development, and ADA research.
• Native Glycosylation — Mammalian expression ensures native-like patterns.
Host species: Mouse
Isotype: IgG2a-kappa
Species reactivity: Human
Immunogen:
Form: Liquid
Storage instructions:
Storage buffer: 0.01M PBS, pH7.4.
Concentration: 1mg/ml
Purity: >95% as determined by SDS-PAGE.
Clonality: Monoclonal
Applications: Research Grade Biosimilar
Target: Epithelialglycoprotein314,hEGP314,Majorgastrointestinaltumor-associatedproteinGA733-2,EGP314,TACSTD1,Adenocarcinoma-associatedantigen,TROP1,EPCAM,Epithelialglycoprotein,KS1/4antigen,Tumor-associatedcalciumsignaltransducer1,M4S1,CD326,Ep-CAM,EGP,Epithelialcelladhesionmolecule,M1S2,KSA,CellsurfaceglycoproteinTrop-1,GA733-2,Epithelialcellsurfaceantigen,MIC18
Purification: Protein A/G purified from cell culture supernatant.
Endotoxin level: <1EU/mg, determined by LAL gel clotting assay
Expression system: Mammalian Cells
Stability and Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Alternative Names: 17-1A,CAS:156586-89-9
Background: Epithelial cell adhesion molecule (CD326/EPCAM) is a ~34 kDa protein. May act as a physical homophilic interaction molecule between intestinal epithelial cells (IECs) and intraepithelial lymphocytes (IELs) at the mucosal epithelium for providing immunological barrier as a first line of defense against mucosal infection. Plays a role in embryonic stem cells proliferation and differentiation. Up-regulates the expression of FABP5, MYC and cyclins A and E.
Note: For research use only. Not suitable for clinical or therapeutic use.