Human CD66e/CEA/CEACAM5 Recombinant Protein (C-His)

Human CD66e/CEA/CEACAM5 Recombinant Protein (C-His)

  • Catalog number: PH10633
  • Availability: In Stock
  • $298.00

  • Ex Tax: $298.00


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  • Description: Recombinant Human CD66e/CEA/CEACAM5 Protein, C-His (PH10633) expressed in Mammalian Cells, spanning Met1-Ala685.
    Highlights:
    • His-Tagged — N-terminal 6×His tag for IMAC purification.
    • Mammalian Expression — Proper folding and native glycosylation.
    • High Purity — >90% purity verified by SDS-PAGE.
  • Form: Lyophilized
  • Storage buffer: Lyophilized from a solution in PBS pH 7.4, 1mM EDTA, 4% Trehalose, 1% Mannitol.
  • Purity: >90% as determined by SDS-PAGE.
  • Applications: ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
  • Endotoxin level: Please contact with the lab for this information.
  • Expression system: Mammalian Cells
  • Protein length: Met1-Ala685
  • Predicted molecular weight: 72.7 kDa
  • Stability and Storage: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
  • Reconstitution: Reconstitute in sterile water for a stock solution.A copy of datasheet will be provided with the products, please refer to it for details.
  • Alternative Names: Meconium antigen 100, CEACAM5, CEA, CD66e, Carcinoembryonic antigen-related cell adhesion molecule 5, Carcinoembryonic antigen
  • Species: Homo sapiens (Human)
  • Shipping: In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
  • Background: Cell adhesion molecule CEACAM5 (CD66e) is a ~76 kDa protein. Cell surface glycoprotein that plays a role in cell adhesion, intracellular signaling and tumor progression. Mediates homophilic and heterophilic cell adhesion with other carcinoembryonic antigen-related cell adhesion molecules, such as CEACAM6. Plays a role as an oncogene by promoting tumor progression; induces resistance to anoikis of colorectal carcinoma cells.
    References:
    1. Taheri, M. et al. (2000) The Journal of biological chemistry 275, 26935-43. PMID: 10864933
    2. Ordoñez, C. et al. (2000) Cancer research 60, 3419-24. PMID: 1091005
    3. Oikawa, S. et al. (1989) Biochemical and biophysical research communications 164, 39-45. PMID: 2803308
  • Note: For research use only.

Images

  • SDS-PAGE for Human CD66e/CEA/CEACAM5 Recombinant Protein (C-His)
    SDS-PAGE

    SDS-PAGE for Recombinant Human CD66e/CEA/CEACAM5 Protein, C-His

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