Human DSP Recombinant Protein (N-His)
- Catalog number: PH11027
- Availability: In Stock
$211.00
- Ex Tax: $211.00
- Description: Recombinant Human DSP Protein, N-His (PH11027) expressed in E. coli, spanning Phe2609-Ala2822. Purity: >90% by SDS-PAGE.
Highlights:
• His-Tagged — N-terminal 6×His tag for IMAC purification.
• E. coli Expression — High-yield, cost-effective production.
• High Purity — >90% purity verified by SDS-PAGE. - Form: Lyophilized
- Storage buffer: Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
- Purity: >90% as determined by SDS-PAGE.
- Applications: ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
- Endotoxin level: Please contact with the lab for this information.
- Expression system: E. coli
- Protein length: Phe2609-Ala2822
- Predicted molecular weight: 25.58 kDa
- Stability and Storage: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
- Reconstitution: Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
- Alternative Names: 250/210 kDa paraneoplastic pemphigus antigen, Desmoplakin, DSP, DP
- Species: Homo sapiens (Human)
- Shipping: In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
- Background: Desmoplakin (DSP) is a ~331 kDa protein. A component of desmosome cell-cell junctions which are required for positive regulation of cellular adhesion. Critical for cell-cell adhesion in early stage blastocysts and progression through proamniotic cavity formation. Not required for preimplantation morphogenic process in blastocysts. Required for keratin filament anchoring at the desmosome junction and subsequent organization of the keratin intermediate filament network within the cytoplasm. Required for anchoring of desmosomes to the microtubule architecture, via its interaction with NIN.
References:
1. Albrecht, LV. et al. (2015) The Journal of cell biology 208, 597-612. PMID: 25733715
2. Li, P. et al. (2019) International journal of biological sciences 15, 2350-2362. PMID: 31595153 - Note: For research use only.
Images
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SDS-PAGESDS-PAGE for Recombinant Human DSP Protein, N-His
