Anti-Human SOST/Sclerostin Reference Antibody (Setrusumab, RUO)
- Catalog number: BS10391
- Availability: In Stock
$176.00
- Ex Tax: $176.00
Description: Setrusumab (BS10391) is a research-grade recombinant antibody targeting SOST. Produced in mammalian cells with native-like glycosylation.
Highlights:
• Research Grade — For PK/PD studies, assay development, and ADA research.
• Native Glycosylation — Mammalian expression ensures native-like patterns.
Host species: Human
Isotype: IgG2-lambda
Species reactivity: Human
Immunogen:
Form: Liquid
Storage instructions:
Storage buffer: 0.01M PBS, pH7.4.
Concentration: 1mg/ml
Purity: >95% as determined by SDS-PAGE.
Clonality: Monoclonal
Applications: Research Grade Biosimilar
Target: SOST,Sclerostin
Purification: Protein A/G purified from cell culture supernatant.
Endotoxin level: <1EU/mg, determined by LAL gel clotting assay
Expression system: Mammalian Cells
Stability and Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Alternative Names: BPS-804,MOR-05813,CAS:1847394-95-9
Background: Sclerostin (SOST) is a ~24 kDa protein. Negative regulator of bone growth that acts through inhibition of Wnt signaling and bone formation.
Note: For research use only. Not suitable for clinical or therapeutic use.
Highlights:
• Research Grade — For PK/PD studies, assay development, and ADA research.
• Native Glycosylation — Mammalian expression ensures native-like patterns.
Host species: Human
Isotype: IgG2-lambda
Species reactivity: Human
Immunogen:
Form: Liquid
Storage instructions:
Storage buffer: 0.01M PBS, pH7.4.
Concentration: 1mg/ml
Purity: >95% as determined by SDS-PAGE.
Clonality: Monoclonal
Applications: Research Grade Biosimilar
Target: SOST,Sclerostin
Purification: Protein A/G purified from cell culture supernatant.
Endotoxin level: <1EU/mg, determined by LAL gel clotting assay
Expression system: Mammalian Cells
Stability and Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Alternative Names: BPS-804,MOR-05813,CAS:1847394-95-9
Background: Sclerostin (SOST) is a ~24 kDa protein. Negative regulator of bone growth that acts through inhibition of Wnt signaling and bone formation.
Note: For research use only. Not suitable for clinical or therapeutic use.
Images
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SEC-HPLCSEC-HPLC detection for Research Grade Setrusumab.
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SDS-PAGESDS-PAGE for Research Grade Setrusumab.
