Anti-Human MIS RII Reference Antibody (Murlentamab, RUO)

Description: Murlentamab (BS10418) is a research-grade recombinant antibody targeting MIS type II receptor. Produced in mammalian cells with native-like glycosylation.
Highlights:
• Research Grade — For PK/PD studies, assay development, and ADA research.
• Native Glycosylation — Mammalian expression ensures native-like patterns.
Host species: Humanized
Isotype: IgG1-kappa
Species reactivity: Human
Immunogen:
Form: Liquid
Storage instructions:
Storage buffer: 0.01M PBS, pH7.4.
Concentration: 1mg/ml
Purity: >95% as determined by SDS-PAGE.
Clonality: Monoclonal
Applications: Research Grade Biosimilar
Target: MIStypeIIreceptor,MISR2,AMHR2,AMHR,Anti-MuellerianhormonetypeIIreceptor,MRII,AMHtypeIIreceptor,MISRII,Anti-Muellerianhormonetype-2receptor
Purification: Protein A/G purified from cell culture supernatant.
Endotoxin level: <1EU/mg, determined by LAL gel clotting assay
Expression system: Mammalian Cells
Stability and Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Alternative Names: 3C23K,GM102,CAS:2058047-65-5
Background: Anti-Muellerian hormone type-2 receptor (AMHR2) is a ~62 kDa protein. On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Receptor for anti-Muellerian hormone.
Note: For research use only. Not suitable for clinical or therapeutic use.