Anti-Human VEGFA & ANG-2 Bispecific Reference Antibody (Vanucizumab, RUO)
- Catalog number: BS10422
- Availability: In Stock
$176.00
- Ex Tax: $176.00
Description: Vanucizumab (BS10422) is a research-grade recombinant antibody targeting Vascular endothelial growth factor A. Produced in mammalian cells with native-like glycosylation.
Highlights:
• Research Grade — For PK/PD studies, assay development, and ADA research.
• Native Glycosylation — Mammalian expression ensures native-like patterns.
Host species: Humanized
Isotype: VH-C-kappa-CH2-CH3_V-lambda-CH1_H-GAMMA-1_L-kappa
Species reactivity: Human
Immunogen:
Form: Liquid
Storage instructions:
Storage buffer: 0.01M PBS, pH7.4.
Concentration: 1mg/ml
Purity: >95% as determined by SDS-PAGE.
Clonality: Monoclonal
Applications: Research Grade Biosimilar
Target: VascularendothelialgrowthfactorA,VPF,VEGFA,VEGF,Vascularpermeabilityfactor,VEGF-A,ANG-2,ANGPT2,Angiopoietin-2
Purification: Protein A/G purified from cell culture supernatant.
Endotoxin level: <1EU/mg, determined by LAL gel clotting assay
Expression system: Mammalian Cells
Stability and Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Alternative Names: Bispecific,RG-7221,RG7221,RO5520985,CAS:1448221-05-3
Background: Zifibancimig is an anti-VEGFA/ANGPT2 IgG1κ monoclonal antibody.
Note: For research use only. Not suitable for clinical or therapeutic use.
Highlights:
• Research Grade — For PK/PD studies, assay development, and ADA research.
• Native Glycosylation — Mammalian expression ensures native-like patterns.
Host species: Humanized
Isotype: VH-C-kappa-CH2-CH3_V-lambda-CH1_H-GAMMA-1_L-kappa
Species reactivity: Human
Immunogen:
Form: Liquid
Storage instructions:
Storage buffer: 0.01M PBS, pH7.4.
Concentration: 1mg/ml
Purity: >95% as determined by SDS-PAGE.
Clonality: Monoclonal
Applications: Research Grade Biosimilar
Target: VascularendothelialgrowthfactorA,VPF,VEGFA,VEGF,Vascularpermeabilityfactor,VEGF-A,ANG-2,ANGPT2,Angiopoietin-2
Purification: Protein A/G purified from cell culture supernatant.
Endotoxin level: <1EU/mg, determined by LAL gel clotting assay
Expression system: Mammalian Cells
Stability and Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Alternative Names: Bispecific,RG-7221,RG7221,RO5520985,CAS:1448221-05-3
Background: Zifibancimig is an anti-VEGFA/ANGPT2 IgG1κ monoclonal antibody.
Note: For research use only. Not suitable for clinical or therapeutic use.
Images
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BioactivityDetects Human VEGFA in indirect ELISAs.
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BioactivityDetects Human ANGPT2 in indirect ELISAs.
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Flow CytoMetryFlow-cytometry using FITC anti-human VEGFA&ANGPT2 antibody. U87 cells were fixed and permeabilized, then stained with an irrelevant antibody (Blue Histogram) or an FITC anti-human VEGFA&ANGPT2 monoclonal antibody (Catalog: HT073026, Yellow Histogram) at a concentration of 5 µg/ml for 30 mins at RT. After washing, cells analysed on a NovoCyte Flow Cytometer.
