Anti-Phosphatidylserine Reference Antibody (Bavituximab, RUO)
- Catalog number: BS10472
- Availability: In Stock
$176.00
- Ex Tax: $176.00
Description: Bavituximab (BS10472) is a research-grade recombinant antibody targeting Phosphatidylserine. Produced in mammalian cells with native-like glycosylation.
Highlights:
• Research Grade — For PK/PD studies, assay development, and ADA research.
• Native Glycosylation — Mammalian expression ensures native-like patterns.
Host species: Chimeric
Isotype: IgG1-kappa
Species reactivity: General
Immunogen:
Form: Liquid
Storage instructions:
Storage buffer: 0.01M PBS, pH7.4.
Concentration: 1.82mg/ml
Purity: >95% as determined by SDS-PAGE.
Clonality: Monoclonal
Applications: Research Grade Biosimilar
Target: Phosphatidylserine
Purification: Protein A/G purified from cell culture supernatant.
Endotoxin level: <1EU/mg, determined by LAL gel clotting assay
Expression system: Mammalian Cells
Stability and Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Alternative Names: Tarvacinch3G4,CAS:648904-28-3
Background: Bavituximab (Anti-Human Phosphatidylserine Recombinant Antibody) is a phosphatidylserine (PS)-targeting monoclonal antibody, suppresses tumor growth by targeting tumor vasculature and reactivating antitumor immunity. Bavituximab plus Paclitaxel and Carboplatin, have enhanced inhibition on non-small-cell lung cancer.
References:
1. Phosphatidylserine and the human brain., PMID:25933483
2. The distribution and function of phosphatidylserine in cellular membranes., PMID:20192774
2. Phosphatidylserine transport in cell life and death., PMID:37413778
3. Phosphatidylserine., PMID:10541030
5. Phosphatidylserine: A Novel Target for Ischemic Stroke Treatment., PMID:39456225
6. Phosphatidylserine for the Treatment of Pediatric Attention-Deficit/Hyperactivity Disorder: A Systematic Review and Meta-Analysis., PMID:33539192
7. Phosphatidylserine externalization as immune checkpoint in cancer., PMID:38573347
4. Phosphatidylserine: A comprehensive overview of synthesis, metabolism, and nutrition., PMID:39097133
5. Dynamics of phagocytosis mediated by phosphatidylserine., PMID:36281986
10. Flagging fusion: Phosphatidylserine signaling in cell-cell fusion., PMID:33581114
Note: For research use only. Not suitable for clinical or therapeutic use.
Highlights:
• Research Grade — For PK/PD studies, assay development, and ADA research.
• Native Glycosylation — Mammalian expression ensures native-like patterns.
Host species: Chimeric
Isotype: IgG1-kappa
Species reactivity: General
Immunogen:
Form: Liquid
Storage instructions:
Storage buffer: 0.01M PBS, pH7.4.
Concentration: 1.82mg/ml
Purity: >95% as determined by SDS-PAGE.
Clonality: Monoclonal
Applications: Research Grade Biosimilar
Target: Phosphatidylserine
Purification: Protein A/G purified from cell culture supernatant.
Endotoxin level: <1EU/mg, determined by LAL gel clotting assay
Expression system: Mammalian Cells
Stability and Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Alternative Names: Tarvacinch3G4,CAS:648904-28-3
Background: Bavituximab (Anti-Human Phosphatidylserine Recombinant Antibody) is a phosphatidylserine (PS)-targeting monoclonal antibody, suppresses tumor growth by targeting tumor vasculature and reactivating antitumor immunity. Bavituximab plus Paclitaxel and Carboplatin, have enhanced inhibition on non-small-cell lung cancer.
References:
1. Phosphatidylserine and the human brain., PMID:25933483
2. The distribution and function of phosphatidylserine in cellular membranes., PMID:20192774
2. Phosphatidylserine transport in cell life and death., PMID:37413778
3. Phosphatidylserine., PMID:10541030
5. Phosphatidylserine: A Novel Target for Ischemic Stroke Treatment., PMID:39456225
6. Phosphatidylserine for the Treatment of Pediatric Attention-Deficit/Hyperactivity Disorder: A Systematic Review and Meta-Analysis., PMID:33539192
7. Phosphatidylserine externalization as immune checkpoint in cancer., PMID:38573347
4. Phosphatidylserine: A comprehensive overview of synthesis, metabolism, and nutrition., PMID:39097133
5. Dynamics of phagocytosis mediated by phosphatidylserine., PMID:36281986
10. Flagging fusion: Phosphatidylserine signaling in cell-cell fusion., PMID:33581114
Note: For research use only. Not suitable for clinical or therapeutic use.
Images
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BioactivitySEC-HPLC detection for Research Grade Bavituximab.
