Anti-Human CXCR5 Reference Antibody (Sar113244, RUO)

Description: SAR113244 (BS10542) is a research-grade recombinant antibody targeting CD185. Produced in mammalian cells with native-like glycosylation.
Highlights:
• Research Grade — For PK/PD studies, assay development, and ADA research.
• Native Glycosylation — Mammalian expression ensures native-like patterns.
Host species: Humanized
Isotype: IgG4-kappa
Species reactivity: Human
Immunogen:
Form: Liquid
Storage instructions:
Storage buffer: 0.01M PBS, pH7.4.
Concentration: 1mg/ml
Purity: >95% as determined by SDS-PAGE.
Clonality: Monoclonal
Applications: Research Grade Biosimilar
Target: CXC-R5,CD185,MDR-15,C-X-Cchemokinereceptortype5,CXCR5,CXCR-5,MDR15,Monocyte-derivedreceptor15,Burkittlymphomareceptor1,BLR1
Purification: Protein A/G purified from cell culture supernatant.
Endotoxin level: <1EU/mg, determined by LAL gel clotting assay
Expression system: Mammalian Cells
Stability and Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Alternative Names: SAR113244
Background: C-X-C chemokine receptor type 5 (CD185/CXCR5) is a ~41 kDa protein. Cytokine receptor that binds to B-lymphocyte chemoattractant (BLC). Involved in B-cell migration into B-cell follicles of spleen and Peyer patches but not into those of mesenteric or peripheral lymph nodes. May have a regulatory function in Burkitt lymphoma (BL) lymphomagenesis and/or B-cell differentiation.
Note: For research use only. Not suitable for clinical or therapeutic use.