Anti-Human CD40/TNFRSF5 & CD137/TNFRSF9 Bispecific Reference Antibody (Tecaginlimab, RUO)
- Catalog number: BS10772
- Availability: In Stock
$482.00
- Ex Tax: $482.00
Description: Tecaginlimab (BS10772) is a research-grade recombinant antibody targeting CD40. Produced in mammalian cells with native-like glycosylation.
Highlights:
• Research Grade — For PK/PD studies, assay development, and ADA research.
• Native Glycosylation — Mammalian expression ensures native-like patterns.
Host species: Humanized
Isotype: IgG1-kappa
Species reactivity: Human
Immunogen:
Form: Liquid
Storage instructions:
Storage buffer: 0.01M PBS, pH7.4.
Concentration: 1mg/ml
Purity: >95% as determined by SDS-PAGE.
Clonality: Monoclonal
Applications: Research Grade Biosimilar
Target: Tumornecrosisfactorreceptorsuperfamilymember5,B-cellsurfaceantigenCD40,Bp50,CD40Lreceptor,TNFRSF5,CDw40,CD40,Tumornecrosisfactorreceptorsuperfamilymember9,CD137,4-1BBligandreceptor,CDw137,TNFRSF9,T-cellantigenILA,T-cellantigen4-1BBhomolog,ILA
Purification: Protein A/G purified from cell culture supernatant.
Endotoxin level: <1EU/mg, determined by LAL gel clotting assay
Expression system: Mammalian Cells
Stability and Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Alternative Names: Bispecific,BNT-312,DuoBody-CD40x-4-1BB,GEN1042,GEN-1042,GEN1042CAS:2253891-70-0
Background: Tecaginlimab (BNT-312) is a Fc-inert bispecific antibody for dual targeting and conditional stimulation of CD40 and 4-1BB. Tecaginlimab can enhance priming and reactivation of tumor-specific immunity.
Note: For research use only. Not suitable for clinical or therapeutic use.
Highlights:
• Research Grade — For PK/PD studies, assay development, and ADA research.
• Native Glycosylation — Mammalian expression ensures native-like patterns.
Host species: Humanized
Isotype: IgG1-kappa
Species reactivity: Human
Immunogen:
Form: Liquid
Storage instructions:
Storage buffer: 0.01M PBS, pH7.4.
Concentration: 1mg/ml
Purity: >95% as determined by SDS-PAGE.
Clonality: Monoclonal
Applications: Research Grade Biosimilar
Target: Tumornecrosisfactorreceptorsuperfamilymember5,B-cellsurfaceantigenCD40,Bp50,CD40Lreceptor,TNFRSF5,CDw40,CD40,Tumornecrosisfactorreceptorsuperfamilymember9,CD137,4-1BBligandreceptor,CDw137,TNFRSF9,T-cellantigenILA,T-cellantigen4-1BBhomolog,ILA
Purification: Protein A/G purified from cell culture supernatant.
Endotoxin level: <1EU/mg, determined by LAL gel clotting assay
Expression system: Mammalian Cells
Stability and Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Alternative Names: Bispecific,BNT-312,DuoBody-CD40x-4-1BB,GEN1042,GEN-1042,GEN1042CAS:2253891-70-0
Background: Tecaginlimab (BNT-312) is a Fc-inert bispecific antibody for dual targeting and conditional stimulation of CD40 and 4-1BB. Tecaginlimab can enhance priming and reactivation of tumor-specific immunity.
Note: For research use only. Not suitable for clinical or therapeutic use.
Images
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SDS-PAGESDS-PAGE for Research Grade Tecaginlimab.
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Flow CytoMetryFlow-cytometry using APC anti-human CD40 antibody. U2OS cells were stained with an irrelevant antibody (Blue Histogram) or an APC anti-human CD40 monoclonal antibody (Catalog: HB782126, Yellow Histogram) at a concentration of 5 µg/ml for 30 mins at RT. After washing, and cells analysed on a NovoCyte Flow Cytometer.
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Flow CytoMetryFlow-cytometry using PE anti-human CD40 antibody. U2OS cells were stained with an irrelevant antibody (Blue Histogram) or an PE anti-human CD40 monoclonal antibody (Catalog: HB782126, Yellow Histogram) at a concentration of 5 µg/ml for 30 mins at RT. After washing, and cells analysed on a NovoCyte Flow Cytometer.
