Anti-Corynephage omega DT/Diphtheria toxin Reference Antibody (DTD4)

Description: Anti-Corynephage omega DT/Diphtheria toxin Antibody (DTD4) (BS10798) is a research-grade recombinant antibody targeting Diphtheria toxin. Produced in mammalian cells with native-like glycosylation.
Highlights:
• Research Grade — For PK/PD studies, assay development, and ADA research.
• Native Glycosylation — Mammalian expression ensures native-like patterns.
Host species: Human
Isotype: IgG2-kappa
Species reactivity: Corynephageomega
Immunogen:
Form: Liquid
Storage instructions:
Storage buffer: 0.01M PBS, pH7.4.
Concentration: 1mg/ml
Purity: >95% as determined by SDS-PAGE.
Clonality: Monoclonal
Applications: Research Grade Biosimilar
Target: Diphtheriatoxin,DT,NAD(+)--diphthamideADP-ribosyltransferase,2.4.2.36,DiphtheriatoxinfragmentA,DiphtheriatoxinfragmentB
Purification: Protein A/G purified from cell culture supernatant.
Endotoxin level: <1EU/mg, determined by LAL gel clotting assay
Expression system: Mammalian Cells
Stability and Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Alternative Names:
Background: Diphtheria toxin (DT) is a ~60 kDa protein. Diphtheria toxin, produced by a phage infecting Corynebacterium diphtheriae, is a proenzyme that, after activation, catalyzes the covalent attachment of the ADP ribose moiety of NAD to elongation factor 2. Fragment A is responsible for enzymatic ADP-ribosylation of elongation factor 2, while fragment B is responsible for binding of toxin to cell receptors and entry of fragment A.
Note: For research use only. Not suitable for clinical or therapeutic use.