Human USP4 Recombinant Protein (N-His)
- Catalog number: PH16304
- Availability: In Stock
$211.00
- Ex Tax: $211.00
- Description: Recombinant Human USP4 Protein, N-His (PH16304) expressed in E. coli, spanning Asp12-Glu220. Purity: >90% by SDS-PAGE.
Highlights:
• His-Tagged — N-terminal 6×His tag for IMAC purification.
• E. coli Expression — High-yield, cost-effective production.
• High Purity — >90% purity verified by SDS-PAGE. - Form: Lyophilized
- Storage buffer: Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
- Purity: >90% as determined by SDS-PAGE.
- Applications: ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
- Endotoxin level: Please contact with the lab for this information.
- Expression system: E. coli
- Protein length: Asp12-Glu220
- Predicted molecular weight: 26.67 kDa
- Stability and Storage: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
- Reconstitution: Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
- Alternative Names: Ubiquitin carboxyl-terminal hydrolase 4, 3.4.19.12, Deubiquitinating enzyme 4, Ubiquitin thioesterase 4, Ubiquitin-specific-processing protease 4, Ubiquitous nuclear protein homolog, USP4, UNP, UNPH
- Species: Homo sapiens (Human)
- Shipping: In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
- Background: Ubiquitin carboxyl-terminal hydrolase 4 (USP4) is a ~108 kDa protein. Deubiquitinating enzyme that removes conjugated ubiquitin from target proteins. Deubiquitinates PDPK1. Deubiquitinates TRIM21. Deubiquitinates receptor ADORA2A which increases the amount of functional receptor at the cell surface. Deubiquitinates HAS2.
References:
1. Wada, K. et al. (2006) Biochemical and biophysical research communications 339, 731-6. PMID: 16316627
2. Milojevic, T. et al. (2006) Molecular pharmacology 69, 1083-94. PMID: 16339847
3. Wada, K. et al. (2006) Biochemical and biophysical research communications 342, 253-8. PMID: 16472766
4. Song, EJ. et al. (2010) Genes & development 24, 1434-47. PMID: 20595234
5. Uras, IZ. et al. (2012) PloS one 7, e31003. PMID: 2234742
6. Clerici, M. et al. (2014) Nature communications 5, 5399. PMID: 25404403
7. Mehić, M. et al. (2017) Oncogenesis 6, e348. PMID: 28604766
8. Deng, L. et al. (2019) Cell research 29, 136-150. PMID: 30514904
9. Chu, F. et al. (2024) Proceedings of the National Academy of Sciences of the United States of America 121, e2401174121. PMID: 39589880 - Note: For research use only.
Images
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SDS-PAGESDS-PAGE for Recombinant Human USP4 Protein, N-His
