Anti-Human GDF-8/Myostatin Reference Antibody (Apitegromab, RUO)

Description: Apitegromab (BS10856) is a research-grade recombinant antibody targeting GDF-8. Produced in mammalian cells with native-like glycosylation.
Highlights:
• Research Grade — For PK/PD studies, assay development, and ADA research.
• Native Glycosylation — Mammalian expression ensures native-like patterns.
Host species: Human
Isotype: IgG4-Lambda
Species reactivity: Human
Immunogen:
Form: Liquid
Storage instructions:
Storage buffer: 0.01M PBS, pH7.4.
Concentration: 7.48mg/ml
Purity: >95% as determined by SDS-PAGE.
Clonality: Monoclonal
Applications: Research Grade Biosimilar
Target: GDF-8,GDF8,MSTN,Myostatin,Growth/differentiationfactor8
Purification: Protein A/G purified from cell culture supernatant.
Endotoxin level: <1EU/mg, determined by LAL gel clotting assay
Expression system: Mammalian Cells
Stability and Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Alternative Names: SRK015,SRK-015,SRK015,CAS:2278276-46-1
Background: Growth/differentiation factor 8 (pro-MSTN/GDF8) is a ~42 kDa protein. Acts specifically as a negative regulator of skeletal muscle growth.
Note: For research use only. Not suitable for clinical or therapeutic use.