Anti-VSIG4/CRIg Reference Antibody (VTX-1218)
- Catalog number: BS10894
- Availability: In Stock
$370.00
- Ex Tax: $370.00
Highlights:
• Research Grade — For PK/PD studies, assay development, and ADA research.
• Native Glycosylation — Mammalian expression ensures native-like patterns.
Host species: Human
Isotype: IgG1,kappa
Species reactivity: Human
Immunogen:
Form: Liquid
Storage instructions:
Storage buffer: 0.01M PBS, pH7.4.
Concentration: 1.29mg/ml
Purity: >95% as determined by SDS-PAGE.
Clonality: Monoclonal
Applications: Research Grade Biosimilar
Target: ProteinZ39Ig,CRIg,V-setandimmunoglobulindomain-containingprotein4,VSIG4,Z39IG
Purification: Protein A/G purified from cell culture supernatant.
Endotoxin level: <1EU/mg, determined by LAL gel clotting assay
Expression system: Mammalian Cells
Stability and Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Alternative Names:
Background: V-set and immunoglobulin domain-containing protein 4 (VSIG4/CRIg) is a ~43 kDa protein. Phagocytic receptor, strong negative regulator of T-cell proliferation and IL2 production. Potent inhibitor of the alternative complement pathway convertases.
Note: For research use only. Not suitable for clinical or therapeutic use.
Images
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BioactivityDetects VSIG4 in indirect ELISAs.
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SDS-PAGESDS-PAGE for Research Grade Anti-VSIG4/CRIg Antibody (VTX-1218).
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Flow cytometryFlow-cytometry APC using anti-human VSIG4 antibody. Untransfected cells (blue Histogram) and Transfected cells (Yellow Histogram) were stained with an APC anti-human VSIG4 monoclonal antibody (Catalog HP545026) at a concentration of 5 µg/ml for 30 mins at RT. After washing, cells analysed on a NovoCyte Flow Cytometer.
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Flow cytometryFlow-cytometry PE using anti-human VSIG4 antibody. Untransfected cells (blue Histogram) and Transfected cells (Yellow Histogram) were stained with an PE anti-human VSIG4 monoclonal antibody (Catalog HP545026) at a concentration of 5 µg/ml for 30 mins at RT. After washing, cells analysed on a NovoCyte Flow Cytometer.
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Flow cytometryFlow-cytometry FITC using anti-human VSIG4 antibody. Untransfected cells (blue Histogram) and Transfected cells (Yellow Histogram) were stained with an FITC anti-human VSIG4 monoclonal antibody (Catalog HP545026) at a concentration of 5 µg/ml for 30 mins at RT. After washing, cells analysed on a NovoCyte Flow Cytometer.
